Thorne Research 5-MTHF
-1mg & 5 mg
5-MTHF is a highly bioactive form of folic acid.
- Great for pregnancy.
- Cardiovascular Folate Support
- Nervous System Folate support
- Does not include magnesium stearate (an impurity found in many supplements.)
5-MTHF is the active form of folic acid. In order for the body to use folic acid, it must go through a chemical process that converts it. This process takes place in the liver and the large and small intestines. There are many people with liver and intestinal disfunction that doesn't allow this process to take place as eneded. There are other studies that indicate that 33% of the population in the United States may have a genetic defect in an enzyme that doesn't allow them to convert folic acid into the active form of 5-MTHF. For this reason, taking a 5-MTHF supplement makes a lot of sense.
According to the research, supplementing with folic acid will help decrease the risk of many different birth defects. Specifically, the folic acid is required during the nervous system developmenet in the infant. This means that folic acid requirements usually double during prengnacy, which is why supplementation is required by many physicians and OB/GYN's. Many birth defects, such as low birth weight, and neuro complications can be prevented with a healthy folic acid supplement.
Not only is folic acid important when you become pregnant, but it should also be used on a regular basis to maintain your folic acid stores if you are trying to become pregnant. This will ensure that your baby will have plenty of folic acid for when you conceive and the baby starts to mature.
Folic acid must be converted to its active forms to be used by the body.* This is a multi-step biochemical process that occurs in the intestines and liver. In the presence of intestinal or liver dysfunction this conversion may not occur sufficiently enough to meet the body's needs. Furthermore, up to one-third of the U.S. population may have a genetic enzyme defect that makes it difficult for them to convert folic acid (even folinic acid) into active 5-MTHF. For these individuals and many others, 5-MTHF supplementation may be a more effective method of folate repletion.*
Because deficiencies of folic acid have been linked to low-birth-weight infants and neural tube defects, folic acid requirements double during pregnancy.* The Centers for Disease Control and Prevention recommends folic acid supplementation for all women of childbearing age because the biggest need is during the first trimester, when a woman may not even be aware she is pregnant.* Supplementation with the more active form may be preferable.*
In concert with vitamin B12, 5-MTHF functions as a methyl-group donor involved in the conversion of the amino acid homocysteine to methionine.* Methyl-group donation is vital to many biochemical conversion processes, including the synthesis of serotonin, melatonin, and DNA.*
It is important for women of childbearing age to get enough folic acid – not just those who are planning to become pregnant.* Only 50 percent of pregnancies are planned, so any woman who could become pregnant should get enough folic acid every day – especially before conception and during early pregnancy.*
Thorne Research 5-MTHF 1mg Ingredients:
One Capsule Contains:
Folate (as 5-Methyl-tetrahydrofolate) ..........1,000 mcg.
Other Ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule.
May contain one or more of the following hypoallergenic ingredients to fill space – Leucine, Silicon Dioxide.
Thorne Research 5-MTHF 5mg Ingredients:
One Capsule Contains:
Folate (as L-5-Methyltetrahydrofolate*) .............5 mg
Suggested Use: One capsule once to three times daily, or as otherwise directed by a health-care practitioner.
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
Free from Excipients:
This product does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, or artificial colors, sweeteners, or flavors. This product also does not contain lactose, palmitic acid, or magnesium, calcium, or vegetable stearates.
If pregnant, consult your health-care practitioner before using this product.
5-methyl-tetrahydrofolate (5-MTHF) supplementation is not recommended concurrently with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.
Thorne Research is a company that has dedicated itself to the highest standard of quality there is when it comes to the manufacturing of its ingredients. Each and every product utilizes the purest ingredients that are available today. Instead of doing what most manufacturers do, Thorne Research doesnt dilute its products with substances. Instead, they purchase the raw material that is some of the finest quality possible. Since there are very few viable sources for the commercial purchase of vitamins B12, D, K or biotin that arent diluted with substances such as lactose, preservatives such as BHT or cornstarch, Thorne Research uses different processes to make sure that everything they use is the purest, most undiluted source possible. If this product interested you, click here to find more Thorne Research products.